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What is mesothelioma and the types of mesothelioma

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What is mesothelioma and the types of mesothelioma

Mesothelioma (cancer of the mesothelium) is a disease in which cells of the mesothelium become abnormal and divide without control or order. They can invade and damage nearby tissues and organs. Cancer cells can also metastasize (spread) from their original site to other parts of the body. Most cases of mesothelioma begin in the pleura or peritoneum.

There are three types of Mesothelioma :
1.  Pleural Mesothelioma
2. 
Peritoneal (abdominal) Mesothelioma
3. 
Pericardial Mesothelioma

1. Pleural Mesothelioma

Pleural mesothelioma is a disease that affects the lining of the lungs, or lung pleura. Sometimes doctors refer to this disease as mesothelioma of the pleura. It is a common misconception that mesothelioma is a type of primary lung cancer; it is not. Mesothelioma is a cancer of the serous membranes. These membranes enclose a number of organs throughout the midsection of the body, including the lungs. The most common type of mesothelioma is one that affects the serous membranes of the lungs: pleural mesothelioma.

Mesothelioma can also affect the serous membranes surrounding the abdomen, called peritoneal (abdominal) mesothelioma, and the membranes surrounding the heart, or pericardial mesothelioma. When mesothelioma spreads to the lungs from the serous linings of the lungs, abdomen or heart, it is considered secondary lung cancer. Also, pleural mesothelioma is sometimes referred to as an asbestos lung cancer. Technically, this is also incorrect, since it does not originate in the lungs. Asbestosis is a type of asbestos lung disease that does originate in the lungs and is often confused with mesothelioma.

Malignant pleural mesothelioma is the most common type of mesothelioma, making up over two-thirds of all cases. Pleural mesothelioma affects the lining of the lung and chest cavity known as the pleura.
The pleura is made up of the parietal and visceral pleura. The parietal pleura lines the chest wall and diaphragm while the visceral pleura lines the lungs.

Malignant pleural mesotheliomaMalignant pleural mesothelioma is the most common type of mesothelioma, making up over two-thirds of all cases. Pleural mesothelioma affects the lining of the lung and chest cavity known as the pleura.
The pleura is made up of the parietal and visceral pleura. The parietal pleura lines the chest wall and diaphragm while the visceral pleura lines the lungs.

Asbestos fibers work their way into the smallest passageways of the lungs and then into the pleura. Once there, an unknown chemical reaction causes cancerous cell development. As the cells begin to divide abnormally, the pleural lining thickens and excess fluid may accumulate. Pleural thickening gradually contracts the breathing space, causing shortness of breath—often the first symptom for pleural mesothelioma. The fluid, once carefully measured to allow smooth movement between the lungs and other organs, now causes increased pressure, further hindering breathing. This excess fluid is often seen on X-rays, and is referred to as a pleural effusion.

Symptoms of Pleural Mesothelioma
Malignant pleural mesothelioma is the most common type of mesothelioma, making up over two-thirds of all cases. Pleural mesothelioma affects the lining of the lung and chest cavity known as the pleura.
The pleura is made up of the parietal and visceral pleura. The parietal pleura lines the chest wall and diaphragm while the visceral pleura lines the lungs.

Asbestos fibers work their way into the smallest passageways of the lungs and then into the pleura. Once there, an unknown chemical reaction causes cancerous cell development. As the cells begin to divide abnormally, the pleural lining thickens and excess fluid may accumulate. Pleural thickening gradually contracts the breathing space, causing shortness of breath—often the first symptom for pleural mesothelioma. The fluid, once carefully measured to allow smooth movement between the lungs and other organs, now causes increased pressure, further hindering breathing. This excess fluid is often seen on X-rays, and is referred to as a pleural effusion.

Symptoms of pleural mesothelioma (mesothelioma of the lining of the lung, known as the pleura) may include, but are not limited to, the following:

  • shortness of breath (dyspnea) - hoarseness, difficulty swallowing, and/or coughing up of blood.

  • pleural effusion - a build up of too much fluid between the pleura (linings of the lungs and chest); a pleural effusion may cause chest pain and difficulty breathing (dyspnea), however, many cause no symptoms and are first discovered during the physical examination or seen on a chest x-ray.

  • pain in the chest - may sometimes be felt in upper abdomen, shoulder, or arm.

  • Pain in the lower back or the side of the chest

  • A persistent cough

  • Shortness of breath

  • A hoarse or husky voice

  • Losing more than 10% of your weight when not dieting

  • Sweating and fevers

  • Difficulty swallowing

Patients diagnosed with diffuse pleural mesothelioma exhibited the following symptoms :

Symptom

Exhibiting

Shortness of breath and/or chest pain

90%

Weight loss

29%

Cough, weakness, fever, loss of appetite

3%

Hemoptysis (coughing up blood), hoarseness, dysphagia (difficulty swallowing), Horner's syndrome

less than 1%

Pleural Effusions

84%

Asymptomatic

3%

Next : 2. Peritoneal (abdominal) Mesothelioma ; 3. Pericardial Mesothelioma

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